本集主要內容： 原國營221廠研製出了中國第一顆原子彈和氫彈，《代號221》正是講述自1958年以來的幾十年間，我國第一代核工業人在青海金銀灘草原上“做隱姓瞞名人，幹驚天動地事”的那段重要歷史。（《代號221》 第一集 出征）
本集主要內容： 半個多世紀前，羅布泊戈壁深處的東方巨響讓世界為之震驚，然而，很少有人知道，中國最早的原子彈、氫彈在哪研發製造，答案就隱藏在青藏高原的金銀灘。肩負着特殊使命，他們將夢想付諸現實，以熱血和智慧鍛造國之重器，昔日青春芳華，今已耄耋之年，魂牽夢繞的塵封往事是家國無悔的奮鬥誓言，重返歷史現場，一起走進絕密之地。（《代號221》 第二集 巨響）
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