With just six days to go before the UK votes on whether to withdraw from the European Union, the looks increasingly uncertain.

The US Federal Reserve has deferred a decision on interest rates, in part over doubts on Britain’s continued EU membership and EU leaders are warning of a profound shock to the union should the UK quit.

There’s also been a negative impact on the British Pound and the markets ahead of next Thursday's vote.

The White Cliffs of Dover – in British minds an eternal symbol of UK sovereignty and independence.

An emotional bulwark at the heart of so called Brexit.

Defying immigration levels heightened by the European Union’s Freedom of Movement rule.

"That’s a crazy crackpot scheme and the only way we can do anything about that is to get out of the Freedom of Movement Directive and the only way we can do that is to exit the European Union," said local people.

"I’m all for immigration, but this country is getting a bit too over populated."

"All these people coming in, which I’ve got no problem with if they’re working, but a lot of them are not working."

The battle of Brexit took to the waters of the River Thames this week, a flotilla of fishermen lamenting the impact of EU rules on Britain’s fisheries industry.

And in fish processing plants, accusations of Brussels bureaucracy gone bonkers.

"We’ve had to spend thousands of pounds last year on printing new packaging, so that a pack of smoked salmon could have a warning sign on the back saying: 'contains fish.' It’s completely mad," said Lance Foreman Salmon, smokehouse owner.

The giants of British industry however have real worries over leaving the world’s richest trading bloc.

Britain’s gargantuan Rolls Royce Engineering, the latest business to warn of a threat to investment from a vote to quit the EU.

On the land, concern a consistent supply of essential European labour could dry up.

Uncertainty has already hit the Pound and the markets as the world anxiously watches and waits for voters in Britain to have their say.

"It is a decision that could have consequences for economic and financial conditions in global financial markets. If it does so it could have consequences in turn for the U.S. economic outlook," said Janet Yellen, US Federal Reserve chair.

Worse, in an interview with Germany’s prestigious Der Spiegel Magazine, the country’s finance minister, Wolfgang Schaeuble has voiced alarm that Brexit could have a domino effect across the EU.

But it’s here perhaps that the impact is greatest.

In the heat of the Brexit battle, Parliamentary friendships and ancient alliances have become so much collateral damage.

Whatever the outcome next week, it’ll likely take years for those political wounds to heal.